Poor circulation
Growth factors are delivered to the skin through the circulation. Growth factors such as VEGFA are fundamental to sustaining a young skin phenotype. PMID: 35749494.
“I used it every day at night and my skin began to feel plumper and hydrated
Soo Joo Park
“I was always told I had to pick my face or my ass - I never understood what that meant until I got older and lost weight in my face - so this is literally facial Ben and Jerrys - eat up.
Jenna Lyons
“When I first came across Adipeau, I thought this is too good to be true. But after 6 weeks of using it, it 100% lived up to its promise! It’s a truly pioneering cream mask that I’m swearing by now.
Viktorija Svedkova-Jasevice
“I love Adipeau, it's now a critical part of my evening routine! It immediately restored the moisture from my skin, while giving my skin a glow and minimizing my fine lines over time. I noticed it from the very first morning I used it. Very mild, and has a subtle lemon scent to it. Works beautifully on my dry, sensitive skin.
Nelli Kim
“My aesthetician told me to try Adipeau’s cream mask, but I forgot about it. Then after I fell ill and lost too much weight I had very wrinkled crepey skin around my eyes and neck. After just 4 weeks of using the cream mask every day I saw my skin bounce back!
Chantal Hughes
“I’ve been using Adipeau’s cream mask for about 12 weeks. I noticed my wrinkles on forehead and eyes have significantly improved. With continued use, I also noticed my skin feels nice and tight, more plump. I’m hooked!
Helen Costello
“This cream is a game changer. I usually have a very minimal skincare routine, but this will now be added into my daily skincare regime. I have noticed smoother, less red and plump looking skin. I can't say enough about this product.
Rachel baker
“My experience with using adipeau has been fantastic! After losing about 15-20 lbs, the skin on my face, mainly around my jaw and neck, was "drooping" and the overall texture and appearance of my undereyes felt thinner and darker as well. I've been using adipeau for about 5 weeks, and can see the difference! The skin under my chin/jaw definitely looks and feels more taught and my undereyes have plumped up a bit.
Amy Rosenberg
Growth factors are delivered to the skin through the circulation. Growth factors such as VEGFA are fundamental to sustaining a young skin phenotype. PMID: 35749494.
UV rays create inflammation on the skin surface which causes downstream damage to dermal adipocytes (PMID: 27665714).
Procedures that seek to de-nature the dermis (e.g., ultrasound, radiofrequency), preferentially heat up the dermal adipocytes causing rupture and loss, which results in hypertrophy of remaining adipocytes PMID: 19322624
Oils in cosmetic products can be delivered to mature fat cells via the hair follicle, where they are taken up by mature fat cells. PMIDs. 33803716, 18492146.
The increase in adipocyte size seen with age is a function of both higher BMI and lower regeneration rate. PMIDs. 30283987, 33878347.
Lymph fluid is largely comprised of lipid which is taken up by adipocytes, increasing their size. PMID. 34339353
High BMI reflects increased nutrient storage and leads directly to enlarged fat cell size. PMID: 27895989.
A reduction in the number of fat cells causes the size of the remaining fat cells to increases. PMID. 9333196.
Hormones play important roles in regulating fat cell health. Estrogen, for example, is important in maintaining adipogenesis. PMID: 35856485.
Injecting the body with foreign substances like engineered botulinum toxin, cross-linked hyaluronic acid and poly-L lactic acid filler may trigger inflammatory responses that can suppress adipogenesis. In terms of frequency, poly-L lactic acid, then hyaluronic acid then botulinum toxin. PMIDs: 33797747, 20564542, and 21903293.
The most common skincare ingredients – retin-A, resveratrol, and hyaluronic acid – are all anti-adipogenic. PMIDs 35171653, 17851734 and 31151314.
All exercise suppresses new fat cell formation through acute inflammation and also through dynamic force and prolonged exercise has a greater effect than moderate exercise PMID: 32230849.
With age, pre-adipocytes are still converting to mature adipocytes but this process requires a stronger signal PMID: 17507194.
Protein drives regeneration of dermal adipocytes. Insufficient protein consumption is a leading cause of insufficient cell numbers. PMID: 27832138.
UV rays create inflammation on the skin surface which causes downstream damage to dermal adipocytes (PMID: 27665714).